session management with database: optimal parameters in php.ini

I am developping one script for the "session management with database"
and I would like to know which parameters I must change in php.ini
according to these requirements:

- I am using the session_set_save_handler() function
- I don't know if the client side uses or not the cookies
- Several clients can access in the same time to the web application
- The web application shall be secured against classical attacks
.

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